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Yuan, Zuanning, Georgescu, Roxana, Yao, Nina Y., Yurieva, Olga, O’Donnell, Michael E., Li, Huilin (2024) Mechanism of PCNA loading by Ctf18-RFC for leading-strand DNA synthesis. Science, 385 (6708) doi:10.1126/science.adk5901

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Reference TypeJournal (article/letter/editorial)
TitleMechanism of PCNA loading by Ctf18-RFC for leading-strand DNA synthesis
JournalScience
AuthorsYuan, ZuanningAuthor
Georgescu, RoxanaAuthor
Yao, Nina Y.Author
Yurieva, OlgaAuthor
O’Donnell, Michael E.Author
Li, HuilinAuthor
Year2024 (August 2)Volume385
Issue6708
PublisherAmerican Association for the Advancement of Science (AAAS)
DOIdoi:10.1126/science.adk5901Search in ResearchGate
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Mindat Ref. ID17536705Long-form Identifiermindat:1:5:17536705:6
GUID0
Full ReferenceYuan, Zuanning, Georgescu, Roxana, Yao, Nina Y., Yurieva, Olga, O’Donnell, Michael E., Li, Huilin (2024) Mechanism of PCNA loading by Ctf18-RFC for leading-strand DNA synthesis. Science, 385 (6708) doi:10.1126/science.adk5901
Plain TextYuan, Zuanning, Georgescu, Roxana, Yao, Nina Y., Yurieva, Olga, O’Donnell, Michael E., Li, Huilin (2024) Mechanism of PCNA loading by Ctf18-RFC for leading-strand DNA synthesis. Science, 385 (6708) doi:10.1126/science.adk5901
In(2024, August) Science Vol. 385 (6708) American Association for the Advancement of Science (AAAS)

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Zheng, Fengwei, Yao, Nina Y., Georgescu, Roxana E., Li, Huilin, O’Donnell, Michael E. (2024) Structure of the PCNA unloader Elg1-RFC. Science Advances, 10 (9) doi:10.1126/sciadv.adl1739
Yuan, Zuanning, Georgescu, Roxana, Bai, Lin, Zhang, Dan, Li, Huilin, O’Donnell, Michael E. (2020) DNA unwinding mechanism of a eukaryotic replicative CMG helicase. Nature Communications, 11. doi:10.1038/s41467-020-14577-6
He, Qing, Wang, Feng, Yao, Nina Y., O’Donnell, Michael E., Li, Huilin (2024) Structures of the human leading strand Polε–PCNA holoenzyme. Nature Communications, 15 (1). doi:10.1038/s41467-024-52257-x
Yuan, Zuanning, Georgescu, Roxana, Li, Huilin, O’Donnell, Michael E. (2023) Molecular choreography of primer synthesis by the eukaryotic Pol α-primase. Nature Communications, 14 (1) doi:10.1038/s41467-023-39441-1
He, Qing, Wang, Feng, Yao, Nina Y., O’Donnell, Michael E., Li, Huilin (2024) Author Correction: Structures of the human leading strand Polε–PCNA holoenzyme. Nature Communications, 15 (1). doi:10.1038/s41467-024-54128-x
Langston, Lance D., Yuan, Zuanning, Georgescu, Roxana, Li, Huilin, O’Donnell, Michael E. (2022) SV40 T-antigen uses a DNA shearing mechanism to initiate origin unwinding. Proceedings of the National Academy of Sciences, 119 (49) doi:10.1073/pnas.2216240119
Georgescu, Roxana, Yuan, Zuanning, Bai, Lin, de Luna Almeida Santos, Ruda, Sun, Jingchuan, Zhang, Dan, Yurieva, Olga, Li, Huilin, O’Donnell, Michael E. (2017) Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation. Proceedings of the National Academy of Sciences, 114 (5) doi:10.1073/pnas.1620500114
He, Qing, Wang, Feng, O’Donnell, Michael E., Li, Huilin (2024) Cryo-EM reveals a nearly complete PCNA loading process and unique features of the human alternative clamp loader CTF18-RFC. Proceedings of the National Academy of Sciences, 121 (18) doi:10.1073/pnas.2319727121
Zheng, Fengwei, Georgescu, Roxana E., Li, Huilin, O’Donnell, Michael E. (2020) Structure of eukaryotic DNA polymerase δ bound to the PCNA clamp while encircling DNA. Proceedings of the National Academy of Sciences, 117 (48) 30344-30353 doi:10.1073/pnas.2017637117
Yao, Nina Y., Zhang, Dan, Yurieva, Olga, O’Donnell, Michael E. (2022) CMG helicase can use ATPγS to unwind DNA: Implications for the rate-limiting step in the reaction mechanism. Proceedings of the National Academy of Sciences, 119 (4) doi:10.1073/pnas.2119580119
Wang, Feng; He, Qing; O’Donnell, Michael E.; Li, Huilin (2025) The proofreading mechanism of the human leading-strand DNA polymerase ε holoenzyme. Proceedings of the National Academy of Sciences, 122 (22). doi:10.1073/pnas.2507232122
 
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