Qin, Ruihao; Hua, Menglei; Wang, Yaru; Zhang, Qi; Cao, Yong; Dai, Yanyan; Ma, Chenjing; Zheng, Xiaohan; Ge, Kaiyuan; Zhang, Huimin; et al. (2025) Multiomics Investigation of Exhausted T Cells in Glioblastoma Tumor Microenvironment: CCL5 as a Prognostic and Therapeutic Target. International Journal of Molecular Sciences, 26 (20). doi:10.3390/ijms26209920
| Reference Type | Journal (article/letter/editorial) | ||
|---|---|---|---|
| Title | Multiomics Investigation of Exhausted T Cells in Glioblastoma Tumor Microenvironment: CCL5 as a Prognostic and Therapeutic Target | ||
| Journal | International Journal of Molecular Sciences | ||
| Authors | Qin, Ruihao | Author | |
| Hua, Menglei | Author | ||
| Wang, Yaru | Author | ||
| Zhang, Qi | Author | ||
| Cao, Yong | Author | ||
| Dai, Yanyan | Author | ||
| Ma, Chenjing | Author | ||
| Zheng, Xiaohan | Author | ||
| Ge, Kaiyuan | Author | ||
| Zhang, Huimin | Author | ||
| Li, Shi | Author | ||
| Liu, Yan | Author | ||
| Cao, Lei | Author | ||
| Wang, Liuying | Author | ||
| Year | 2025 (October 12) | Volume | 26 |
| Issue | 20 | ||
| Publisher | MDPI AG | ||
| DOI | doi:10.3390/ijms26209920Search in ResearchGate | ||
| Generate Citation Formats | |||
| Mindat Ref. ID | 19087073 | Long-form Identifier | mindat:1:5:19087073:9 |
| GUID | 0 | ||
| Full Reference | Qin, Ruihao; Hua, Menglei; Wang, Yaru; Zhang, Qi; Cao, Yong; Dai, Yanyan; Ma, Chenjing; Zheng, Xiaohan; Ge, Kaiyuan; Zhang, Huimin; et al. (2025) Multiomics Investigation of Exhausted T Cells in Glioblastoma Tumor Microenvironment: CCL5 as a Prognostic and Therapeutic Target. International Journal of Molecular Sciences, 26 (20). doi:10.3390/ijms26209920 | ||
| Plain Text | Qin, Ruihao; Hua, Menglei; Wang, Yaru; Zhang, Qi; Cao, Yong; Dai, Yanyan; Ma, Chenjing; Zheng, Xiaohan; Ge, Kaiyuan; Zhang, Huimin; et al. (2025) Multiomics Investigation of Exhausted T Cells in Glioblastoma Tumor Microenvironment: CCL5 as a Prognostic and Therapeutic Target. International Journal of Molecular Sciences, 26 (20). doi:10.3390/ijms26209920 | ||
| In | (2025, October) International Journal of Molecular Sciences Vol. 26 (20). MDPI AG | ||
References Listed
These are the references the publisher has listed as being connected to the article. Please check the article itself for the full list of references which may differ. Not all references are currently linkable within the Digital Library.
| Not Yet Imported: - journal-article : 10.1038/s41577-019-0221-9 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1016/j.immuni.2023.05.008 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1016/j.immuni.2020.04.014 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
 | Pauken, K. E., Sammons, M. A., Odorizzi, P. M., Manne, S., Godec, J., Khan, O., Drake, A. M., Chen, Z., Sen, D. R., Kurachi, M., Barnitz, R. A., Bartman, C., Bengsch, B., Huang, A. C., Schenkel, J. M., Vahedi, G., Haining, W. N., Berger, S. L., Wherry, E. J. (2016) Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade. Science, 354 (6316). 1160-1165 doi:10.1126/science.aaf2807 |
| Not Yet Imported: - journal-article : 10.1038/s41571-022-00689-z If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| |
| Noor, L., Upadhyay, A., and Joshi, V. (2024). Role of T Lymphocytes in Glioma Immune Microenvironment: Two Sides of a Coin. Biology, 13. | |
| Not Yet Imported: Nature Reviews Immunology - journal-article : 10.1038/nri.2016.144 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1158/1078-0432.CCR-19-1068 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1093/neuonc/noad149 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: Cellular Physiology and Biochemistry - journal-article : 10.1159/000438532 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1038/s41419-018-0343-1 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1158/1078-0432.CCR-17-1846 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| |
| Not Yet Imported: Cell Death & Disease - journal-article : 10.1038/s41419-021-03533-x If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: Nanomedicine: Nanotechnology, Biology and Medicine - journal-article : 10.1016/j.nano.2019.102112 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.3390/cancers15051562 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1016/j.cell.2014.12.033 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1080/1744666X.2023.2198209 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1172/jci.insight.152731 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1038/s41419-021-03973-5 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: Molecular Cell - journal-article : 10.1016/j.molcel.2023.12.039 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1093/nar/gkac616 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Kamphorst, Alice O., Wieland, Andreas, Nasti, Tahseen, Yang, Shu, Zhang, Ruan, Barber, Daniel L., Konieczny, Bogumila T., Daugherty, Candace Z., Koenig, Lydia, Yu, Ke, Sica, Gabriel L., Sharpe, Arlene H., Freeman, Gordon J., Blazar, Bruce R., Turka, Laurence A., Owonikoko, Taofeek K., Pillai, Rathi N., Ramalingam, Suresh S., Araki, Koichi, Ahmed, Rafi (2017) Rescue of exhausted CD8 T cells by PD-1–targeted therapies is CD28-dependent. Science, 355 (6332). 1423-1427 doi:10.1126/science.aaf0683 |
| Not Yet Imported: Nature Reviews Immunology - journal-article : 10.1038/s41577-022-00792-3 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1016/j.immuni.2016.04.020 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1371/journal.pgen.1002078 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1016/j.scr.2012.09.002 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1016/j.cytogfr.2024.02.001 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| |
| Not Yet Imported: Molecular Cancer - journal-article : 10.1186/s12943-023-01900-0 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: Nature Reviews Immunology - journal-article : 10.1038/nri.2016.49 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1038/s41418-019-0460-0 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.3390/medicina58020203 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1038/s41420-018-0063-4 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1016/j.immuni.2023.06.007 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1016/j.cell.2017.08.004 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: Cancer Cell - journal-article : 10.1016/j.ccell.2019.05.004 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: Cancers - journal-article : 10.3390/cancers12010018 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1016/j.stem.2017.10.002 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Hart (2013) Cochrane Database Syst. Rev. Temozolomide for high grade glioma 2013, CD007415 | |
| Not Yet Imported: Current Molecular Pharmacology - journal-article : 10.2174/1874467211205010102 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Xu (2024) Cell Death Dis. Glioblastoma stem cells deliver ABCB4 transcribed by ATF3 via exosomes conferring glioblastoma resistance to temozolomide 15, 318 | |
| Not Yet Imported: Journal of Nanobiotechnology - journal-article : 10.1186/s12951-023-01801-w If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Peralta (2024) Nat. Immunol. Dysfunction of exhausted T cells is enforced by MCT11-mediated lactate metabolism 25, 2297 | |
| Jeon (2024) Clin. Cancer Res. Anti–4-1BB×PDL1 Bispecific Antibody Reinvigorates Tumor-Specific Exhausted CD8+ T Cells and Enhances the Efficacy of Anti-PD1 Blockade 30, 4155 | |
| Not Yet Imported: Annals of Medicine - journal-article : 10.1080/07853890.2023.2205168 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Wu (2024) Signal Transduct. Target. Ther. Cold and hot tumors: From molecular mechanisms to targeted therapy 9, 274 | |
| Zheng (2025) Int. J. Immunopathol. Pharmacol. High expression of CCL3/CCL4/CCL5/CCR5 promotes exhausted CD8(+) T cells terminal differentiation and is associated with poor prognosis in pediatric B-ALL patients 39, 3946320251346823 | |
| Not Yet Imported: - journal-article : 10.1111/imr.12616 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1038/s41551-021-00737-6 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: Immunology - journal-article : 10.1111/imm.13557 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Ma (2021) Am. J. Transl. Res. TNFSF13B and PPARGC1A expression is associated with tumor-infiltrating immune cell abundance and prognosis in clear cell renal cell carcinoma 13, 11048 | |
| Not Yet Imported: Case Reports in Oncology - journal-article : 10.1159/000514190 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: Neurosurgical Review - journal-article : 10.1007/s10143-022-01839-8 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Trefny, Marcel P., Kirchhammer, Nicole, Auf der Maur, Priska, Natoli, Marina, Schmid, Dominic, Germann, Markus, Fernandez Rodriguez, Laura, Herzig, Petra, Lötscher, Jonas, Akrami, Maryam, Stinchcombe, Jane C., Stanczak, Michal A., Zingg, Andreas, Buchi, Melanie, Roux, Julien, Marone, Romina, Don, Leyla, Lardinois, Didier, Wiese, Mark, Jeker, Lukas T., Bentires-Alj, Mohamed, Rossy, Jérémie, Thommen, Daniela S., Griffiths, Gillian M., Läubli, Heinz, Hess, Christoph, Zippelius, Alfred (2023) Deletion of SNX9 alleviates CD8 T cell exhaustion for effective cellular cancer immunotherapy. Nature Communications, 14 (1) doi:10.1038/s41467-022-35583-w |
| Zhu (2024) Int. Immunopharmacol. The significance of CD8(+) tumor-infiltrating lymphocytes exhaustion heterogeneity and its underlying mechanism in diffuse large B-cell lymphoma 137, 112447 | |
| Not Yet Imported: - journal-article : 10.1080/2162402X.2021.2010905 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Araujo, Jhajaira M., Gomez, Andrea C., Aguilar, Alfredo, Salgado, Roberto, Balko, Justin M., Bravo, Leny, Doimi, Franco, Bretel, Denisse, Morante, Zaida, Flores, Claudio, Gomez, Henry L., Pinto, Joseph A. (2018) Effect of CCL5 expression in the recruitment of immune cells in triple negative breast cancer. Scientific Reports, 8. doi:10.1038/s41598-018-23099-7 |
| Kanehisa (2024) Nucleic Acids Res. KEGG: Biological systems database as a model of the real world 53, D672 | |
| Not Yet Imported: Nucleic Acids Research - journal-article : 10.1093/nar/gkac1010 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1038/ng.3823 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.7554/eLife.34408 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1016/j.gpb.2020.10.005 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| |
| Not Yet Imported: - journal-article : 10.1101/gr.165126.113 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| |
| Not Yet Imported: EMBO reports - journal-article : 10.15252/embr.202050612 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.3389/fimmu.2023.1139517 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.4049/jimmunol.140.7.2171 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1038/nm.2446 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1177/0962280210394459 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1371/journal.pmed.1003288 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1186/s12916-023-03142-9 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Chen (2016) F1000Res From reads to genes to pathways: Differential expression analysis of RNA-Seq experiments using Rsubread and the edgeR quasi-likelihood pipeline 5, 1438 | |
| Not Yet Imported: - journal-article : 10.1093/bioinformatics/btp616 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1016/j.ccell.2022.05.004 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1186/s13059-022-02648-4 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Ishwaran (2008) J. Thorac. Oncol. Off. Publ. Int. Assoc. Study Lung Cancer Random survival forests 2, 841 | |
| Not Yet Imported: Proceedings of the 22nd ACM SIGKDD International Conference on Knowledge Discovery and Data Mining - proceedings-article : 10.1145/2939672.2939785 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| |
| Not Yet Imported: - journal-article : 10.1158/1538-7445.AM2020-LB-242 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1038/s43018-022-00356-3 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1038/s41587-019-0114-2 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| |
| Not Yet Imported: Genome Biology - journal-article : 10.1186/s13059-017-1349-1 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - book-chapter : 10.1007/978-1-0716-0327-7_17 If you would like this item imported into the Digital Library, please contact us quoting Book ID 9781071603260 | |
| Not Yet Imported: - journal-article : 10.7554/eLife.26476 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Lindskrog, Sia Viborg, Prip, Frederik, Lamy, Philippe, Taber, Ann, Groeneveld, Clarice S., Birkenkamp-Demtröder, Karin, Jensen, Jørgen Bjerggaard, Strandgaard, Trine, Nordentoft, Iver, Christensen, Emil, Sokac, Mateo, Birkbak, Nicolai J., Maretty, Lasse, Hermann, Gregers G., Petersen, Astrid C., Weyerer, Veronika, Grimm, Marc-Oliver, Horstmann, Marcus, Sjödahl, Gottfrid, Höglund, Mattias, Steiniche, Torben, Mogensen, Karin, de Reyniès, Aurélien, Nawroth, Roman, Jordan, Brian, Lin, Xiaoqi, Dragicevic, Dejan, Ward, Douglas G., Goel, Anshita, Hurst, Carolyn D., Raman, Jay D., Warrick, Joshua I., Segersten, Ulrika, Sikic, Danijel, van Kessel, Kim E. M., Maurer, Tobias, Meeks, Joshua J., DeGraff, David J., Bryan, Richard T., Knowles, Margaret A., Simic, Tatjana, Hartmann, Arndt, Zwarthoff, Ellen C., Malmström, Per-Uno, Malats, Núria, Real, Francisco X., Dyrskjøt, Lars (2021) An integrated multi-omics analysis identifies prognostic molecular subtypes of non-muscle-invasive bladder cancer. Nature Communications, 12 (1) doi:10.1038/s41467-021-22465-w |
| Not Yet Imported: - journal-article : 10.1158/0008-5472.CAN-17-0307 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: Genome Biology - journal-article : 10.1186/s13059-016-1028-7 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.7150/thno.73235 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: Genome Biology - journal-article : 10.1186/s13059-022-02844-2 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1038/s41477-023-01406-z If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: - journal-article : 10.1002/cyto.a.24496 If you would like this item imported into the Digital Library, please contact us quoting Journal ID | |
| Not Yet Imported: Science Immunology - journal-article : 10.1126/sciimmunol.ade3369 If you would like this item imported into the Digital Library, please contact us quoting Journal ID |
See Also
These are possibly similar items as determined by title/reference text matching only.