Log InRegister
Quick Links : The Mindat ManualThe Rock H. Currier Digital LibraryMindat Newsletter [Free Download]
Home PageAbout MindatThe Mindat ManualHistory of MindatCopyright StatusWho We AreContact UsAdvertise on Mindat
Donate to MindatCorporate SponsorshipSponsor a PageSponsored PagesMindat AdvertisersAdvertise on Mindat
Learning CenterWhat is a mineral?The most common minerals on earthInformation for EducatorsMindat ArticlesThe ElementsThe Rock H. Currier Digital LibraryGeologic Time
Minerals by PropertiesMinerals by ChemistryMineral Visual ExplorerAdvanced Locality SearchRandom MineralRandom LocalitySearch by minIDLocalities Near MeSearch ArticlesSearch GlossaryMore Search Options
Search For:
Mineral Name:
Locality Name:
Keyword(s):
 
The Mindat ManualAdd a New PhotoRate PhotosLocality Edit ReportCoordinate Completion ReportAdd Glossary Item
Mining CompaniesStatisticsUsersMineral MuseumsClubs & OrganizationsMineral Shows & EventsThe Mindat DirectoryDevice SettingsThe Mineral QuizTime Machine
Photo SearchPhoto GalleriesSearch by ColorPhoto Colour ExplorerNew Photos TodayNew Photos YesterdayMembers' Photo GalleriesPast Photo of the Day GalleryPhotography

AL-rasheedi, Zaid F.; Nour, Omnia A.; El-Kashef, Dalia H. (2026) Vonoprazan mitigates diethyl nitrosamine-induced acute liver injury in mice via modulating p-AMPK/ SIRT1/ PGC-1α and Keap1/Nrf2/HO-1 pathways. Life Sciences, 392. doi:10.1016/j.lfs.2026.124314

Advanced
   -   Only viewable:
Reference TypeJournal (article/letter/editorial)
TitleVonoprazan mitigates diethyl nitrosamine-induced acute liver injury in mice via modulating p-AMPK/ SIRT1/ PGC-1α and Keap1/Nrf2/HO-1 pathways
JournalLife Sciences
AuthorsAL-rasheedi, Zaid F.Author
Nour, Omnia A.Author
El-Kashef, Dalia H.Author
Year2026 (May)Volume392
PublisherElsevier BV
DOIdoi:10.1016/j.lfs.2026.124314Search in ResearchGate
Generate Citation Formats
Mindat Ref. ID19722425Long-form Identifiermindat:1:5:19722425:2
GUID0
Full ReferenceAL-rasheedi, Zaid F.; Nour, Omnia A.; El-Kashef, Dalia H. (2026) Vonoprazan mitigates diethyl nitrosamine-induced acute liver injury in mice via modulating p-AMPK/ SIRT1/ PGC-1α and Keap1/Nrf2/HO-1 pathways. Life Sciences, 392. doi:10.1016/j.lfs.2026.124314
Plain TextAL-rasheedi, Zaid F.; Nour, Omnia A.; El-Kashef, Dalia H. (2026) Vonoprazan mitigates diethyl nitrosamine-induced acute liver injury in mice via modulating p-AMPK/ SIRT1/ PGC-1α and Keap1/Nrf2/HO-1 pathways. Life Sciences, 392. doi:10.1016/j.lfs.2026.124314
In(2026) Life Sciences Vol. 392. Elsevier BV

References Listed

These are the references the publisher has listed as being connected to the article. Please check the article itself for the full list of references which may differ. Not all references are currently linkable within the Digital Library.

Trefts (2022) Role and regulation of hepatic metabolism during exercise
Not Yet Imported: - journal-article : 10.1007/s11356-022-23139-w

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: - journal-article : 10.1016/j.phymed.2024.155353

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: Seminars in Liver Disease - journal-article : 10.1055/s-0042-1755274

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: Laboratory Animals - journal-article : 10.1177/0023677215570086

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: - journal-article : 10.1093/carcin/bgab099

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: - journal-article : 10.1080/01635581.2011.523806

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Chain (2023) EFSA J. Risk assessment of N-nitrosamines in food 21
Not Yet Imported: - journal-article : 10.1002/tox.22616

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: - journal-article : 10.1016/j.molcel.2017.05.032

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: - journal-article : 10.3892/mmr.2022.12922

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: - journal-article : 10.1038/s41420-023-01636-2

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: - journal-article : 10.1016/j.ccr.2013.11.005

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: - journal-article : 10.1016/j.biopha.2021.111834

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: - journal-article : 10.3389/fphar.2019.01597

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: - journal-article : 10.1016/S0002-9440(10)63365-2

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: - journal-article : 10.1152/physrev.00023.2017

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Zhou (2022) Front. Cell Dev. Biol. The Nrf2 pathway in liver diseases 10, 2022
Not Yet Imported: - journal-article : 10.2147/DDDT.S255427

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Elsabaawy (2024) Prz Gastroenterol. Vonoprazan a novel potassium competitive acid blocker; another leap forward 19, 135
Not Yet Imported: Drug Design, Development and Therapy - journal-article : 10.2147/DDDT.S276704

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: - journal-article : 10.1016/j.jsps.2022.01.007

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: International Hepatology Communications - journal-article : 10.1016/0928-4346(96)00256-3

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: - journal-article : 10.1016/j.jhep.2019.03.004

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: World Journal of Hepatology - journal-article : 10.4254/wjh.v15.i1.19

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Gan (2025) Signal Transduct. Target. Ther. Liver diseases: epidemiology, causes, trends and predictions 10, 33
Not Yet Imported: Nutrients - journal-article : 10.3390/nu11112673

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: - journal-article : 10.1016/j.scitotenv.2020.142121

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Rahmani (2024) Funct. Foods Health Dis. Therapeutic potential of resveratrol, a polyphenol in the prevention of liver injury induced by diethylnitrosamine (DEN) through the regulation of inflammation and oxidative stress 14
Romualdo, Guilherme Ribeiro, Heidor, Renato, Bacil, Gabriel Prata, Moreno, Fernando Salvador, Barbisan, Luís Fernando (2023) Past, present, and future of chemically induced hepatocarcinogenesis rodent models: Perspectives concerning classic and new cancer hallmarks. Life Sciences, 330. Elsevier BV. 121994 doi:10.1016/j.lfs.2023.121994
Not Yet Imported: - journal-article : 10.1016/j.etp.2014.07.002

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Mao, Jingxin, Tan, Lihong, Tian, Cheng, Wang, Wenxiang, Zhang, Hao, Zhu, Zhaojing, Li, Yan (2024) Research progress on rodent models and its mechanisms of liver injury. Life Sciences, 337. 122343 doi:10.1016/j.lfs.2023.122343
Not Yet Imported: - journal-article : 10.4067/S0716-97602010000100013

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: - journal-article : 10.3390/antiox12051075

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: - journal-article : 10.1097/MOL.0b013e328328d0a4

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: - journal-article : 10.36468/pharmaceutical-sciences.638

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: Aging and disease - journal-article : 10.14336/AD.2018.0513

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: - journal-article : 10.1002/med.21257

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research - journal-article : 10.1016/j.bbamcr.2018.02.010

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: - journal-article : 10.4103/epj.epj_79_23

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: The Journal of Immunology - journal-article : 10.4049/jimmunol.166.11.6812

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Kim (2024) Front. Immunol. Fexuprazan safeguards the esophagus from hydrochloric acid-induced damage by suppressing NLRP1/Caspase-1/GSDMD pyroptotic pathway 15
Not Yet Imported: - journal-article : 10.1016/j.neuropharm.2013.11.004

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Husain, Hadiya, Latief, Uzma, Ahmad, Riaz (2018) Pomegranate action in curbing the incidence of liver injury triggered by Diethylnitrosamine by declining oxidative stress via Nrf2 and NFκB regulation. Scientific Reports, 8. doi:10.1038/s41598-018-26611-1
Not Yet Imported: - journal-article : 10.1080/01635581.2014.894092

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Rahmani (2024) Food Sci. Nutr. The cardiovascular protective function of natural compounds through AMPK/SIRT1/PGC-1α signaling pathway 12, 9998
Not Yet Imported: - journal-article : 10.1039/D2FO02688K

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Sun (2025) bioRxiv AMPK activation prevents hepatocellular carcinoma development through inhibition of HNF4α activity
Not Yet Imported: - journal-article : 10.3389/fendo.2020.00400

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Xu (2024) Heliyon Recent advances in anti-inflammation via AMPK activation 10
Not Yet Imported: Kidney International - journal-article : 10.1016/j.kint.2020.09.037

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: - journal-article : 10.1016/j.tem.2013.12.001

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: - journal-article : 10.1007/s10571-020-00923-1

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: - journal-article : 10.3390/nu14194017

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Not Yet Imported: - journal-article : 10.1155/2022/1949718

If you would like this item imported into the Digital Library, please contact us quoting Journal ID
Rafacho (2015) Hepatobiliary Surg. Nutr. Inhibition of diethylnitrosamine-initiated alcohol-promoted hepatic inflammation and precancerous lesions by flavonoid luteolin is associated with increased sirtuin 1 activity in mice 4, 124

See Also

These are possibly similar items as determined by title/reference text matching only.

El-Kashef, Dalia H., Serrya, Marwa S. (2019) Sitagliptin ameliorates thioacetamide-induced acute liver injury via modulating TLR4/NF-KB signaling pathway in mice. Life Sciences, 228. 266-273 doi:10.1016/j.lfs.2019.05.019
Samaha, Mahmoud M., Nour, Omnia A., Sewilam, Haitham M., El-Kashef, Dalia H. (2023) Diacerein mitigates adenine-induced chronic kidney disease in rats: Focus on TLR4/MYD88/TRAF6/NF-κB pathway. Life Sciences, 331. 122080 doi:10.1016/j.lfs.2023.122080
Abduh, Maisa Siddiq, Alruhaimi, Reem S., Alqhtani, Haifa A., Hussein, Omnia E., Abukhalil, Mohammad H., Kamel, Emadeldin M., Mahmoud, Ayman M. (2023) Rosmarinic acid mitigates chlorpyrifos-induced oxidative stress, inflammation, and kidney injury in rats by modulating SIRT1 and Nrf2/HO-1 signaling. Life Sciences, 313. 121281 doi:10.1016/j.lfs.2022.121281
Luo, Lianxiang, Huang, Fangfang, Zhong, Saiyi, Ding, Rui, Su, Jiating, Li, Xiaoling (2022) Astaxanthin attenuates ferroptosis via Keap1-Nrf2/HO-1 signaling pathways in LPS-induced acute lung injury. Life Sciences, 311. 121091 doi:10.1016/j.lfs.2022.121091
El-Kashef, Dalia H., El-Sheakh, Ahmed R. (2019) Hepatoprotective effect of celecoxib against tamoxifen-induced liver injury via inhibiting ASK-1/JNK pathway in female rats. Life Sciences, 231. 116573pp. doi:10.1016/j.lfs.2019.116573
Cao, Xuejing, Cheng, Jiuxiang, Yang, Yongshou, Wang, Jingmin, Wang, Yongzhong (2025) Arginine-derived carbon dots with antioxidant activity for treating aflatoxin B1-induced liver injury via Nrf2/Keap1 and NLRP3 pathways in mice. Life Sciences, 364. doi:10.1016/j.lfs.2025.123430
Arab, Hany H., Ashour, Ahmed M., Eid, Ahmed H., Arafa, El-Shaimaa A., Al Khabbaz, Hana J., Abd El-Aal, Sarah A. (2022) Targeting oxidative stress, apoptosis, and autophagy by galangin mitigates cadmium-induced renal damage: Role of SIRT1/Nrf2 and AMPK/mTOR pathways. Life Sciences, 291. 120300pp. doi:10.1016/j.lfs.2021.120300
Sharawy, Maha H., Abdelrahman, Rehab S., El-Kashef, Dalia H. (2018) Agmatine attenuates rhabdomyolysis-induced acute kidney injury in rats in a dose dependent manner. Life Sciences, 208. 79-86 doi:10.1016/j.lfs.2018.07.019
Saleh, Ahmed K., El-Mahdy, Nageh A., El-Masry, Thanaa A., El-Kadem, Aya H. (2024) Trifluoperazine mitigates cyclophosphamide-induced hepatic oxidative stress, inflammation, and apoptosis in mice by modulating the AKT/mTOR-driven autophagy and Nrf2/HO-1 signaling cascades. Life Sciences, 344. 122566 doi:10.1016/j.lfs.2024.122566
Marzook, Hezlin; Dawuod, Omama I.; Mohammed, Abdul Khader; Karim, Asima; Taneera, Jalal; Saleh, Mohamed A.; Qaisar, Rizwan; Ahmad, Firdos (2026) GSK-3α activation mitigates Doxorubicin-induced cardiomyopathy through Keap1/Nrf2/HO-1 axis. Life Sciences, 392. doi:10.1016/j.lfs.2026.124317
Kamel, Nada M., El-Sayed, Sarah S., Ali, Shimaa O., Sayed, Rabab H., Safwat, Maheera H. (2025) Linagliptin mitigates lipopolysaccharide-induced acute kidney injury in mice: Novel renal BDNF/TrkB/NRF2-dependent antioxidant, anti-inflammatory, and antiapoptotic mechanisms. Life Sciences, 371. doi:10.1016/j.lfs.2025.123602
 
and/or  
Mindat.org® is an outreach project of the Hudson Institute of Mineralogy, a 501(c)(3) not-for-profit organization. Mindat® and mindat.org® are registered trademarks of the Hudson Institute of Mineralogy.
Copyright © mindat.org and the Hudson Institute of Mineralogy 1993-2026, except where stated. Most political location boundaries are © OpenStreetMap contributors. Mindat.org relies on the contributions of thousands of members and supporters. Founded in 2000 by Jolyon Ralph and Ida Chau.
To cite: Ralph, J., Von Bargen, D., Martynov, P., Zhang, J., Que, X., Prabhu, A., Morrison, S. M., Li, W., Chen, W., & Ma, X. (2025). Mindat.org: The open access mineralogy database to accelerate data-intensive geoscience research. American Mineralogist, 110(6), 833–844. doi:10.2138/am-2024-9486.
Privacy Policy - Terms & Conditions - Contact Us / DMCA issues - Report a bug/vulnerability Current server date and time: June 5, 2026 23:29:35
Go to top of page